Effect of synbiotic supplementation on growth, immunity and intestinal morphometry of broiler chickens in summer season
2
Keywords:
Chickens, Growth, Histopathology, Immunity, SynbioticAbstract
To ascertain the effect of synbiotic supplementation on growth, immunity and intestinal morphometry in broiler chicken during summer season, one hundred sixty-day old Vencobb chicks were randomly allocated into five treatments. Each treatment has 32 birds consisting 4 replicates of 8 birds each. T0: Basal diet; T1: Basal diet + AGP (Salinomycin); T2: Basal diet + prebiotic [Mannan oligosaccharides (MOS)]; T3: Basal diet + probiotic (Lactoplus) and T4: Basal diet+ symbiotic (MOS + Lactoplus). The birds were reared in three phases: pre starter phase (0-1 wk), starter phase (2-3 wks) and finisher phase (4-5 wks) and fed as per BIS (2007). The experiment was continued for the period of 35 days. Gain in body weight, FCR, immunity, morphometry of intestine and histology of liver and kidney was studied. There was significant effect on body weight and FCR following the supplementation of synbiotic. The antibody titre against Ranikhet disease vaccine and the CBH reaction against PHA-P was much greater (p<0.05) in birds which underwent synbiotic supplementation than in the control group. Significant improvement in intestinal villi length, villi width and crypt depth was observed in symbiotic supplemented birds. Histology of liver and kidney showed normal architecture. It may be concluded that synbiotic supplementation in broiler chicken improved the production performance, immunity and intestinal morphometry without any adverse effect on vital organs.
Downloads
References
Abd El‐Hack M E, El‐Saadony M T, Shafi M E, Qattan S Y, Batiha G E, Khafaga A F, Abdel‐Moneim A M and Alagawany M. 2020. Probiotics in poultry feed: A comprehensive review. Journal of Animal Physiology and Animal Nutrition 104(6):1835-50.
Abdallah A G, El-Husseiny O M and Abdel-Latif K O. 2009. Influence of some dietary organic mineral supplementation on broiler performance. International Journal of Poultry Science 8(3): 291-8.
Abdel-Raheem S M, Abd-Allah S M and Hassanein K M. 2012. The effects of prebiotic, probiotic and synbiotic supplementation on intestinal microbial ecology and histomorphology of broiler chickens. International Journal for Agro Veterinary and Medical Sciences 6(4):277-89.
Alagawany M, Abd El-Hack M E, Farag M R, Sachan S, Karthik K and Dhama K. 2018. The use of probiotics as eco-friendly alternatives for antibiotics in poultry nutrition. Environmental Science and Pollution Research 25(11):10611-8.
Ali N A, Jameel Y and Abbas R J. 2019. Effects of dietary prebiotics (SafMannan) and local Iraqi prebiotic on some blood biochemical parameters of broiler chickens. Pakistan Journal of Nutrition 18(1):80-85.
Al-Sultan S I, Abdel-Raheem S M, El-Ghareeb W R and Mohamed M H. 2016. Comparative effects of using prebiotic, probiotic, synbiotic and acidifier on growth performance, intestinal microbiology and histomorphology of broiler chicks. Japanese Journal of Veterinary Research 64(Suppl. 2): S187-95.
Ashayerizadeh A, Dabiri N, Mirzadeh K H and Ghorbani M R. 2011. Effect of dietary supplementation of probiotic and prebiotic on growth indices and serum biochemical parameters of broiler chickens. Journal of Cell and Animal Biology 5(8):152-6.
Ashraf S, Zaneb H, Yousaf M S, Ijaz A, Sohail M U, Muti S, Usman M M, Ijaz S and Rehman H. 2013. Effect of dietary supplementation of prebiotics and probiotics on intestinal microarchitecture in broilers reared under cyclic heat stress. Journal of Animal Physiology and Animal Nutrition 97:68-73.
Awad W A, Ghareeb K, Abdel-Raheem S and Böhm J. 2009. Effects of dietary inclusion of probiotic and synbiotic on growth performance, organ weights, and intestinal histomorphology of broiler chickens. Poultry Science 88(1): 49-56.
Bogucka J, Ribeiro D M, Bogusławska‐Tryk M, Dankowiakowska A, da Costa R P and Bednarczyk M. 2019. Microstructure of the small intestine in broiler chickens fed a diet with probiotic or synbiotic supplementation. Journal of Animal Physiology and Animal Nutrition 103(6):1785-91.
BIS. 2007. Nutrient Requirements of Poultry. Bureau of Indian Standards, 5th revision, New Delhi, India.
Edelman A S, Sanchez P L, Robinson M E, Hochwald G M and Thorbecke G J. 1986. Primary and secondary wattle swelling response to phytohemagglutinin as a measure immunocompetence in chickens. Avian Diseases 105:11.
Ghasemi H A and Taherpour K. 2013. Comparative effects of probiotic, prebiotic and synbiotic supplements on performance, jejunal morphology, serum lipid profile and antibody response of broiler chicks. Journal of Livestock Science and Technologies 1(2):20-7.
Hanamanta H N, Swamy M N, Veena T, Jayakumar K, Swamy H N.2011. Effect of prebiotic and probiotics on growth performance in broiler chickens. Indian Journal of Animal Research, 45 (4) : 271 - 275, 2011
Hassanein S M and Soliman N K. 2010. Effect of probiotic (Saccharomyces cerevisiae) adding to diets on intestinal microflora and performance of Hy-Line layers hens. Journal of American Science 6(11):159-69.
Hassanpour H, Moghaddam A Z, Khosravi M and Mayahi M. 2013. Effects of synbiotic on the intestinal morphology and humoral immune response in broiler chickens. Livestock Science 153(1-3):116-22.
Oi M K, El-Komy A A and Farag E A. 2021. Pharmacological effect of synbiotic and phytobiotic in kidney function and some blood parameters of chicken. International Journal of Pharmacology and Toxicology 9(1):65-74.
Patterson J A and Burkholder K M. 2003. Application of prebiotics and probiotics in poultry production. Poultry Science 82(4):627-31.
Rehman A, Arif M, Sajjad N, Al-Ghadi M Q, Alagawany M, Abd El-Hack M E, Alhimaidi A R, Elnesr S S, Almutairi B O, Amran R A and Hussein E O. 2020. Dietary effect of probiotics and prebiotics on broiler performance, carcass, and immunity. Poultry Science 99(12):6946-53.
Salehimanesh A, Mohammadi M and Roostaei‐Ali Mehr M. 2016. Effect of dietary probiotic, prebiotic and synbiotic supplementation on performance, immune responses, intestinal morphology and bacterial populations in broilers. Journal of Animal Physiology and Animal Nutrition 100(4):694-700.
Salvi P S and Cowles R A. 2021. Butyrate and the intestinal epithelium: Modulation of proliferation and inflammation in homeostasis and disease. Cells 10:1775.
Snedecor G W and Cochran W G. 1994. Statistical Methods. 8th edn. Iowa State University Press, Iowa, USA.
Song D, Li A, Wang Y, Song G, Cheng J, Wang L, Liu K, Min Y and Wang W. 2022. Effects of synbiotic on growth, digestibility, immune and antioxidant performance in broilers. Animal 16(4):100497.
Syafwan S, Kwakkel R P and Verstegen MW. 2011. Heat stress and feeding strategies in meat-type chickens. World's Poultry Science Journal 67(4):653-74.
Submitted
Published
Issue
Section
License
Copyright (c) 2026 The Indian Journal of Animal Sciences

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
The copyright of the articles published in The Indian Journal of Animal Sciences is vested with the Indian Council of Agricultural Research, which reserves the right to enter into any agreement with any organization in India or abroad, for reprography, photocopying, storage and dissemination of information. The Council has no objection to using the material, provided the information is not being utilized for commercial purposes and wherever the information is being used, proper credit is given to ICAR.