Microarray analysis of gene expression profiles of pig muscle in  response to cold stress

Dongjie Zhang; Di Liu; Liang Wang; Wentao Wang; Xinmiao He; Guowei Yang

doi:10.56093/ijans.v82i9.23678

Authors

Dongjie Zhang Heilongjiang Academy of Agriculture Science, Harbin, Heilongjiang, P R 150086 China
Di Liu Heilongjiang Academy of Agriculture Science, Harbin, Heilongjiang, P R 150086 China
Liang Wang Heilongjiang Academy of Agriculture Science, Harbin, Heilongjiang, P R 150086 China
Wentao Wang Heilongjiang Academy of Agriculture Science, Harbin, Heilongjiang, P R 150086 China
Xinmiao He Heilongjiang Academy of Agriculture Science, Harbin, Heilongjiang, P R 150086 China
Guowei Yang Heilongjiang Academy of Agriculture Science, Harbin, Heilongjiang, P R 150086 China

https://doi.org/10.56093/ijans.v82i9.23678

Keywords:

Cold stress, Gene expression, Microarray, Muscle

Abstract

Ambient temperature is a critical factor that affects biological organisms in many ways. In this study, the authors investigated gene expression changes in Min pig muscle in response to cold stress. Female Min pigs were randomly divided into control and cold-stressed groups. Control group was housed at 10±2°C; the cold-stressed group was housed at –20±3°C for 13 days. The results showed that 34 genes were differentially expressed, of which 7 genes were significantly upregulated and 27 genes were significantly downregulated. Subsequent bioinformatics analyses revealed that the differentially expressed genes were mainly related to immune response, response to virus, and RNA binding. The bioinformatics analysis of the differentially expressed genes should be beneficial to further investigations on the underlying mechanisms involved in cold stress–induced damage in the muscle.

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