Characterization of Akirin 2 gene in Langshan chicken
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Authors
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LINJUN YAN
Institute of Cellular and Molecular Biology, Jiangsu Normal University, Xuzhou, Jiangsu 221 116 China
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XINGTANG FANG
Institute of Cellular and Molecular Biology, Jiangsu Normal University, Xuzhou, Jiangsu 221 116 China
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YAO LIU
Institute of Cellular and Molecular Biology, Jiangsu Normal University, Xuzhou, Jiangsu 221 116 China
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MAURICIO A. ELZO
University of Florida, Gainesville, Florida 32611 USA
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HONG CHEN
Nantong Agricultural College (Nantong) Jiangsu 226007 China
Keywords:
Akirin 2, Langshan chicken, MutationAbstract
Akirin play an important role not only in innate immune response but also in skeletal myogenesis. The chicken’s Akirin gene family only has Akirin 2. We detected the coding sequences of the Akirin 2 gene in a Chinese indigenous chicken (Langshan chicken) population to investigate the possibility of using this gene for chicken marker-assisted selection. The results of PCR-SSCP and DNA sequence showed that there were no polymorphisms in the six amplified regions of the Akirin 2 gene. In addition, there was no SNP record about the chicken’s Akirin 2 gene by searching in NCBI. Thus, the Akirin 2 gene may not be suitable to be used in chicken as a gene marker for marker- assisted selection.
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References
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