Association between IGF-1 gene polymorphism and milk production traits in Polish Red-and-White cattle
297 / 109
Keywords:
ACRS-PCR, Cows, IGF-1 gene, Milk, PolymorphismAbstract
The aim of this study was to analyze polymorphism C– 512T in the IGF-1 gene in relation to milk production traits in Polish Red-and-White cattle. Traits analyzed were: milk yield, content of fat, protein, lactose, dry matter and somatic cell count. Polymorphism analysis showed presence of 2 alleles in the investigated herd with frequency C – 0.51, T – 0.49. Association analysis showed that cows with CC and CT genotypes are characterized by higher milk yield in the second lactation comparing to those with TT genotype. Moreover, CC genotype was favorable for somatic cell count.
Downloads
References
Bonakdar E, Rahmani, H R, Edriss M A, and Sayed Tabatabaei B E. 2010. IGF-I gene polymorphism, but not its blood concentration, is associated with milk fat and protein in Holstein dairy cows. Genetics and Molecular Research 9 (3): 1726–34. DOI: https://doi.org/10.4238/vol9-3gmr874
Cummins S B, Waters S M, Evans A C, Lonergan P and Butler S T. 2012. Genetic merit for fertility traits in Holstein cows:3. Hepatic expression of somatotrophic axis genes during pregnancy and lactation. Journal of Dairy Science 95 (7): 3711–21. DOI: https://doi.org/10.3168/jds.2011-4977
Curi R A, de Oliveira H N, Silveira A C and Lopes C R. 2005. Association between IGF-1, IGF-IR and GHRH gene polymorphisms and growth and carcass traits in beef cattle. Livestock Production Science 94 (3): 159–67. DOI: https://doi.org/10.1016/j.livprodsci.2004.10.009
Ge W, Davis M E and Hines H C. 1997. Two SSCP alleles detected in the 5'-flanking region of bovine IGF1 gene. Animal Genetics 28 (2): 155–56.
Ge W, Davis M E, Hines H C and Simmen R C. 2001. Association of a genetic marker with blood serum insulin-like growth factor-I concentration and growth traits in Angus cattle. Journal of Animal Science 79 (7): 1757–62. DOI: https://doi.org/10.2527/2001.7971757x
Gronostajski R M. 2000. Roles of the NFI/CTF gene family in transcription and development, Gene 249 (1–2): 31–35. DOI: https://doi.org/10.1016/S0378-1119(00)00140-2
Grzelak T, Kmieæ M, Wojdak-Maksymiec K, Kulig H and Kowalewska-£uczak I. 2007. IGF-1/SnaBI gene polymorphism in Jersey cows. Proceedings of 2nd Polish Congress of Genetics. pp. 76–77, 18–20 September 2007, Warsaw.
Hines H C, Ge W, Zhao Q and Davis M E. 1998. Association of genetic markers in growth hormone and insulin-like growth factor I loci with lactation traits in Holsteins. Animal Genetics 29 (1): 69–74.
Kirkpatrick B W. 1992. Identification of a conserved microsatellite site in the porcine and bovine insulin-like growth factor-1 gene 5’ flank. Animal Genetics 23 (6): 543–48. DOI: https://doi.org/10.1111/j.1365-2052.1992.tb00176.x
Klauziñska M, ¯urkowski M, Siadkowska E, Szymanowska M, Grochowska R, Zwierzchowski L and Klewiec J. 2004. Analysis of genetic structure in Polish Red and Polish Black- and-White cattle using twelve marker loci potentially related to milk or meat production traits. Animal Science Papers and Reports 22 (2): 153–71.
Lirón J P, Prando A J, Fernndez M E, Ripoli M V, Rogberg-Muñoz A, Goszczynski D E, Posik D M, Peral-García P, Baldo A and Giovambattista G. 2012. Association between GNRHR, LHR and IGF1 polymorphisms and timing of puberty in male Angus cattle. BMC Genetics 13 (26): 1–6. DOI: https://doi.org/10.1186/1471-2156-13-26
Liu K, Muse S V. 2005. PowerMarker: an integrated analysis environment for genetic marker analysis. Bioinformatics 21 (9): 2128–29. DOI: https://doi.org/10.1093/bioinformatics/bti282
Maj A, Snochowski M, Siadkowska E,, Rowinska B, Lisowski P, Robakowska-Hyzorek D, Oprzadek J, Grochowska R, Kochman K and Zwierzchowski L. 2008. Polymorphism in genes of growth hormone receptor (GHR) and insulin-like growth factor-1 (IGF1) and its association with both the IGF1 expression in liver and its level in blood in Polish Holstein-Friesian cattle. Neuro Endocrinology Letters 29 (6): 981–89.
McCarthy S D, Butler S T, Patton J, Daly M, Morris D G, Kenny D A and Waters S M. 2009. Differences in the expression of genes involved in the somatotropic axis in divergent strains of Holstein-Friesian dairy cows during early and mid lactation. Journal of Dairy Science 92 (10): 5229–38. DOI: https://doi.org/10.3168/jds.2008-1856
Mehmannavaz Y, Amirinia C, Bonyadi M and Torshizi R V. 2010. Association of IGF-I gene polymorphism with milk production traits and paternal genetic trends in Iranian Holstein bulls. African Journal of Microbiology Research 4 (1): 110–14.
Mullen M P, Berry D P, Howard D J, Diskin M G, Lynch C O, Giblin L, Kenny D A, Magee D A, Meade K G and Waters S M. 2011. Single Nucleotide Polymorphisms in the Insulin- Like Growth Factor 1 (IGF-1) Gene are Associated with Performance in Holstein-Friesian Dairy Cattle. Frontiers Genetics 2 (3): 1–9. DOI: https://doi.org/10.3389/fgene.2011.00003
Polasik D, Adamska P, Wojdak-Maksymiec K and Kmieæ M, Terman. 2010. Polymorphism of IGF-1 gene in Holstein- Fresian cows. Acta Scientarum Polonorum Zootechnica 9 (4): 199–206.
Reyna X F, Montoya H M, Castrellón V V, Rincón A M, Bracamonte M P and Vera W A. 2010. Polymorphisms in the IGF1 gene and their effect on growth traits in Mexican beef cattle. Genetics and Molecular Research 9 (2) 875–83. DOI: https://doi.org/10.4238/vol9-2gmr745
Siadkowska E, Zwierzchowski L, Oprz¹dek J, Strza³kowska N., Bagnicka E and Krzy¿ewski J. Effect of polymorphism in IGF- 1 gene on production traits in Polish Holstein-Friesian cattle. Animal Science Papers and Reports 24 (3): 225–37.
Szewczuk M, Zych S, Czerniawska-Piatkowska E and Wójcik J. 2012. Association between IGF1R/i16/TaqI and IGF1/SnaBI polymorphisms and milk production traits in Polish Holstein- Friesian cows. Animal Science Papers and Reports 30 (1): 13–24. DOI: https://doi.org/10.5194/aab-54-10-2011
Downloads
Submitted
Published
Issue
Section
License
Copyright (c) 2014 The Indian Journal of Animal Sciences

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The copyright of the articles published in The Indian Journal of Animal Sciences is vested with the Indian Council of Agricultural Research, which reserves the right to enter into any agreement with any organization in India or abroad, for reprography, photocopying, storage and dissemination of information. The Council has no objection to using the material, provided the information is not being utilized for commercial purposes and wherever the information is being used, proper credit is given to ICAR.