Genetic polymorphism of bone morphogenetic protein receptor type-1 gene in Black Bengal goat and its association with litter size

RAJNI KUMARI; SHANKER DAYAL; SANJAY KUMAR; S V LAL; ASIT CHAKRABORTI; S K BARARI; AMITAVA DEY

doi:10.56093/ijans.v85i5.48555

Authors

RAJNI KUMARI Scientist, ICAR Research Complex for Eastern Region, Patna, Bihar 800 014 India
SHANKER DAYAL Senior Scientist, ICAR Research Complex for Eastern Region, Patna, Bihar 800 014 India
SANJAY KUMAR Assistant Professor-cum-Junior Scientist, Department of Animal Nutrition, Bihar Veterinary College, Patna
S V LAL SMS Animal Science, Nimbudera, ICAR-CIARI, Port Blair
ASIT CHAKRABORTI Senior Scientist, ICAR Research Complex for Eastern Region, Patna, Bihar 800 014 India
S K BARARI Chief Technical Officer, ICAR Research Complex for Eastern Region, Patna, Bihar 800 014 India
AMITAVA DEY Principal Scientist and Head, Division of Livestock and Fishery Management, ICAR Research Complex for Eastern Region, Patna, Bihar 800 014 India

https://doi.org/10.56093/ijans.v85i5.48555

Keywords:

Association, Black Bengal goat, BMPR1B gene, Litter size

Abstract

The genetic polymorphism of the bone morphogenetic protein receptor type-1 gene (BMPR1B) was studied in 100 does of Black Bengal goats. The study revealed 2 genetic variants, A (0.25) and G (0.75) and 2 genotypes, AG (0.5) and GG (0.5). Genotypic and allelic frequencies at BMPR1B locus revealed the abundance of mutant type (G) nucleotide in Black Bengal goats. All animals, were found to carry the mutant allele. A positive correlation was observed between the litter size and mutant type genotype. Heterozygous carrier and homozygous carrier does had litter size of 1.6 ± 0.26 and 2.07 ± 0.28 respectively. The results showed that BMPR1 B polymorphism may be targeted for upgrading low prolific breeds of Indian goat by introgression of this mutation in non prolific breeds by crossing.

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