Screening for bovine leukocyte adhesion deficiency, deficiency of uridine monophosphate synthase, bovine citrullinaemia and factor XI deficiency in Holstein cattle

MUHAMMET KAYA; HASAN MEYDAN; ZEKERIYA KIYMA; MUHAMMET ALAN; MEHMET A YILDIZ

doi:10.56093/ijans.v86i8.60794

Authors

MUHAMMET KAYA Eskisehir Osmangazi University, Eskisehir 26480 Turkey
HASAN MEYDAN Eskisehir Osmangazi University, Eskisehir 26480 Turkey
ZEKERIYA KIYMA Eskisehir Osmangazi University, Eskisehir 26480 Turkey
MUHAMMET ALAN Ankara University, Ankara, Turkey
MEHMET A YILDIZ Ankara University, Ankara, Turkey

https://doi.org/10.56093/ijans.v86i8.60794

Keywords:

BC, BLAD, DUMPS, FXID, Holstein cattle, PCR-RFLP

Abstract

Holstein cattle reared in Eskisehir region were monitored with respect to the genetic disorders defined as bovine leukocyte adhesion deficiency (BLAD), deficiency of uridine monophosphate synthase (DUMPS), bovine citrullinaemia (BC) and factor XI deficiency (FXID). To determine the presence of BLAD, DUMPS, BC and FXID genotypes, Holstein cattle (219) were sampled. Three BLAD and 2 FXID carriers were identified among the 219 Holstein cattle examined, while none of the cows carried DUMPS and BC. Current study demonstrated that carriers of BLAD and FXID are present in the Turkish Holstein population in Eskisehir region, although at a low frequency. Since, artificial insemination is widely used in these populations, determination of the carriers of hereditary disorders within the population of breeding sires has become essential. To prevent economic losses resulting from genetic disorders, it is advised to screen breeding sires for these genotypes. The aim of this study was to investigate existence and prevalence of BLAD, DUMPS, BC and FXID alleles in Holstein cattle reared in Eskisehir region by using PCR and PCR-RFLP methods.

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