Evaluation of antiviral and cytotoxic potential of ethanolic extract of Acacia nilotica against peste des petits ruminants virus in vitro cell culture
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Authors
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R RAHEEL
University of Veterinary and Animal Sciences, Lahore 54000, Pakistan
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M ASHRAF
University of Veterinary and Animal Sciences, Lahore 54000, Pakistan
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A JAVEED
University of Veterinary and Animal Sciences, Lahore 54000, Pakistan
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R BASHIR
Lahore College for Women University, Lahore, Pakistan
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N MUNIR
Lahore College for Women University, Lahore, Pakistan
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I ALTAF
University of Veterinary and Animal Sciences, Lahore 54000, Pakistan
Keywords:
Acacia nilotica, Ethanolic extract, MTT assay, Peste des petits ruminants virusAbstract
The present study was designed to determine the cytotoxic and antiviral potential of ethanolic extract of Acacia nilotica leaves, pods and bark against PPRV by using MTT [3–(4,5–dimethylthiazol–2-yl)–2,5-diphenylte- trazolium bromide] colorimetric assay. Antiviral property of ethanolic extract of leaves was higher as compared to pods and bark at its non-cytotoxic concentrations. This plant might be a good source to isolate effective antiviral agents against PPRV.
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References
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