BMP2 gene is a direct target gene of miR-378 in cattle

TENG-HE MA; GUAN-HUI LIU; DONG-MEI LIN; BIN WANG; LONG CHENG; YU-XIANG SHI

doi:10.56093/ijans.v87i6.71188

BMP2 gene is a direct target gene of miR-378 in cattle

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Authors

TENG-HE MA Hebei University of Engineering, Handan 056 021 China
GUAN-HUI LIU Hebei University of Engineering, Handan 056 021 China
DONG-MEI LIN Hebei University of Engineering, Handan 056 021 China
BIN WANG Hebei University of Engineering, Handan 056 021 China
LONG CHENG Hebei University of Engineering, Handan 056 021 China
YU-XIANG SHI Hebei University of Engineering, Handan 056 021 China

https://doi.org/10.56093/ijans.v87i6.71188

Keywords:

BMP2, miRNA, miR-378, Target gene

Abstract

In this study, dual luciferase assay was emplyed to validate whether the BMP2 is a direct target gene of bovine miR-378. miR-378 mimics had extremely significant effects on the luciferase activity of wild BMP2 3’-UTR, but had no effect on the mutated BMP2 3’-UTR. Our result indicated BMP2 is a direct target gene of bovine miR-378.

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References

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Submitted

2017-06-19

Published

2017-06-21

Issue

Vol. 87 No. 6 (2017)

Section

Short-Communication

License

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The copyright of the articles published in The Indian Journal of Animal Sciences is vested with the Indian Council of Agricultural Research, which reserves the right to enter into any agreement with any organization in India or abroad, for reprography, photocopying, storage and dissemination of information. The Council has no objection to using the material, provided the information is not being utilized for commercial purposes and wherever the information is being used, proper credit is given to ICAR.

How to Cite

MA, T.-H., LIU, G.-H., LIN, D.-M., WANG, B., CHENG, L., & SHI, Y.-X. (2017). BMP2 gene is a direct target gene of miR-378 in cattle. The Indian Journal of Animal Sciences, 87(6), 768–769. https://doi.org/10.56093/ijans.v87i6.71188