Metabolism and immune status during transition period influences the lactation performance in Zebu (Bos indicus) cows

PRATIK RAMESH WANKHADE; AYYASAMY MANIMARAN; ARUMUGAM KUMARESAN; SAKTHIVEL JEYAKUMAR; KEREKOPPA P RAMESHA; VEERASAMY SEJIAN; DURAISAMY RAJENDRAN; MADIAJAGAN BAGATH; MUNIANDY SIVARAM

doi:10.56093/ijans.v88i9.83556

Authors

PRATIK RAMESH WANKHADE Research Scholar, Southern Regional Station, ICAR-National Dairy Research Institute, Adugodi, Bengaluru Karnataka 560 030 India
AYYASAMY MANIMARAN Scientist, Southern Regional Station, ICAR-National Dairy Research Institute, Adugodi, Bengaluru Karnataka 560 030 India
ARUMUGAM KUMARESAN Principal Scientist, Livestock Research Centre (LRC), Southern Regional Station, ICAR-National Dairy Research Institute, Adugodi, Bengaluru Karnataka 560 030 India
SAKTHIVEL JEYAKUMAR Principal Scientist, Livestock Research Centre (LRC), Southern Regional Station, ICAR-National Dairy Research Institute, Adugodi, Bengaluru Karnataka 560 030 India
KEREKOPPA P RAMESHA Principal Scientist and Head, Southern Regional Station, ICAR-National Dairy Research Institute, Adugodi, Bengaluru Karnataka 560 030 India
VEERASAMY SEJIAN Senior Scientist, Division of Animal Physiology, Southern Regional Station, ICAR-National Dairy Research Institute, Adugodi, Bengaluru Karnataka 560 030 India
DURAISAMY RAJENDRAN Principal Scientist, Division of Animal Nutrition, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bengaluru, Karnataka.
MADIAJAGAN BAGATH Scientist, Division of Animal Nutrition, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bengaluru, Karnataka
MUNIANDY SIVARAM Senior Scientist, Southern Regional Station, ICAR-National Dairy Research Institute, Adugodi, Bengaluru Karnataka 560 030 India

https://doi.org/10.56093/ijans.v88i9.83556

Keywords:

Acute phase proteins, Deoni cows, Energy indicators, Inflammatory cytokines, Milk yield, Transition period

Abstract

We evaluated the changes in the concentration of innate immune molecules (haptoglobin: Hp, serum amyloid A: SAA, IL-6, TNF-α, IL-1β, and IL-8), energy indicators [NEFA, dry matter intake (DMI) and body condition scoring (BCS)] during the transition period in dual-purpose Zebu (Deoni breed) cows in relation to milk yield. Blood collection was done at weekly intervals (–21±2, –14±1, –7±1, d pre-partum, day 0 (date of calving) and 3±1, 7±1, 14±1, 21±2 d postpartum period) for estimation of above plasma variables using commercially available bovine specific ELISA kits. We also recorded DMI and BCS during the corresponding period. Transition cows were classified based on their milk yield during the study period as high (6), medium (6) and low (6) yielding cows and data were analyzed by using Mixed-model repeated measure analysis. High yielding (HY) cows had significantly higher concentrations of SAA, TNF-α, and IL-6 during pre-partum and early postpartum period than low yielding (LY) cows. DMI was significantly higher in HY cows than MY (3rd and 7th d) or LY cows (21st d) while, BCS was significantly higher in HY than LY cows during pre-partum period (-7th d). LY cows had significantly higher concentration of NEFA during the postpartum period (14th and 21st d). It is concluded that the active functioning of the immune system and more dry matter intake in transition Deoni cows enabled to synthesise more milk during the postpartum period.

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