Assessment of lipid profile and acute phase protein in Mycobacterium avium subspecies paratuberculosis infected and healthy goats

SHALINI SHARMA; SHOOR VIR SINGH; AJAY KUMAR GAUTAM; SUMIT RANJAN MISHRA; SAURABH GUPTA; KUNDAN KUMAR CHAUBEY; NIRMAL SANGWAN

doi:10.56093/ijans.v89i12.96621

Authors

SHALINI SHARMA Assisant Professor, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, Haryana 125 001 India
SHOOR VIR SINGH Professor and Head, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, Haryana 125 001 India
AJAY KUMAR GAUTAM Senior Research Fellow, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, Haryana 125 001 India
SUMIT RANJAN MISHRA PhD Scholar, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, Haryana 125 001 India
SAURABH GUPTA Senior Research Officer, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, Haryana 125 001 India
KUNDAN KUMAR CHAUBEY Senior Research Officer, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, Haryana 125 001 India
NIRMAL SANGWAN Professor-cum-DHRM, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, Haryana 125 001 India

https://doi.org/10.56093/ijans.v89i12.96621

Keywords:

Acute phase proteins, Johneâ€™s disease, Lipid profiling, Mycobacterium avium, Paratuberculosis

Abstract

Present study is based on 24 goats that were located in goat herds endemically infected with Mycobacterium avium subspecies paratuberculosis (MAP) infection. Objective of the study was to access the variations in the lipid profile and acute phase proteins in the serum samples driven from non-infected (negative and physically healthy) and infected (positive and physically weak) goats with MAP infection, cause of incurable Johneâ€™s disease (JD) in domestic livestock. Infected goats had significantly higher cholesterol and albumin levels and significantly â€˜reduced levelâ€™ of high density lipoprotein (HDL) and â€˜reduced levelâ€™ of the density of lipoproteins (LDL) in comparison to non-infected goats. Lipid profile and acute phase proteins could be further explored for their significance in pathogenesis and diagnosis of JD in domestic livestock including goats.

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