Genetic variation at the TVB locus in Turkish and Iranian native chicken breeds
Abstract views: 170
/ 
PDF downloads: 56
Authors
-
MUHAMMET KAYA
Assistant Professor, Department of Agricultural Biotechnology, Eskisehir Osmangazi University, TR-26160, Eskisehir, Turkey
-
HASAN MEYDAN
Associate Professor, Department of Agricultural Biotechnology, Faculty of Agriculture, Akdeniz University, Antalya 07058, Turkey
-
CAFER PISH JANG
PhD Student, Department of Animal Science, Islamic Azad University of Maragheh, Maragheh 11369, Iran
-
MEHMET ALI YILDIZ
Professor, Department of Animal Science, Faculty of Agriculture, Ankara University, Ankara 06100, Turkey
Keywords:
Iran native chicken breeds, PCR-RFLP, Tumor virus B locus, Turkish native chicken breedsAbstract
Avian leukosis viruses (ALVs) are retroviruses that can induce tumors, as well as reduce growth rate and productivity in chicken. The tumor virus B (TVB) locus encodes the cellular receptor that mediates an infection through ALVB, ALVD, and ALVE subgroups of ALV. Two single nucleotide polymorphisms (SNPs) at nucleotide positions 172 and 184 of the autosomal TVB locus account for the three alleles, TVB*S1, TVB*S3, and TVB*R. The receptor encoded by TVB*R allele prevents viral entry into the cell of ALVB, ALVD, or ALVE subgroups. In this study, both SNPs at the TVB locus of 2 Turkish and 7 Iranian native chicken breeds were investigated by using a PCR-RFLP technique to determine genotypes and gene frequencies at TVB locus. The frequency of TVB*S1, and TVB*S3 alleles changed from 0.857 to 1.000, and from 0.022 to 0.143, respectively, in all studied breeds. The TVB*R allele for resistance to ALV-related viruses was not determined. As a result, it can be concluded that Turkish and Iranian native chickens are strongly susceptible to the infection of ALV-related viruses.
Downloads
References
Adkins H B, Blacklow S C and Young J A T. 2001. Two functionally distinct forms of a retroviral receptor explain the nonreciprocal receptor interference among subgroups B, D, and E Avian Leukosis Viruses. Journal of Virology 75(8): 3520–26. DOI: https://doi.org/10.1128/JVI.75.8.3520-3526.2001
Chatterjee R N. 2013. Annual Report 2012–2013. Retrieved in September, 10, 2018 from http://www.pdonpoultry.org/ pdpnew/images/extfiles/reports/NLV12_2.pdf.
Coffin J M, Hughes S H and H E V. 1997. Retroviruses. Cold Spring Harbor Laboratory Press. Cold Spring Harbor, New York.
Nair V and Fadly A M. 2013. Leukosis-sarcoma group, pp. 553– 592. Disease of Poultry. (Eds) Y M Saif, H J Barnes, J R Glisson, A M Fadly, L R McDougald and D E Swayne. American Association of Avian Pathologists, Kennett Square, PA, USA.
Kaya M. 2018. Türkiye Yerli Tavuk Irklarinda Tümör Viral B Lokusunun Belirlenmesi. Kafkas Universitesi Veteriner Fakultesi Dergisi 24(2): 239–42. DOI: https://doi.org/10.9775/kvfd.2017.18769
Liao C T, Chen S Y, Chen W G, Liu Y, Sun B L, Li H X, Zhang H M, Qu H, Wang J, Shu D M and Xie Q M. 2014. Single nucleotide polymorphism variants within TVA and TVB receptor genes in Chinese chickens. Poultry Science 93(10): 2482–89. DOI: https://doi.org/10.3382/ps.2014-04077
Min F and Xiquan Z. 2016. Immunity to Avian Leukosis Virus: Where are we now and what should we do? Frontiers in Immunology 1: 624
Nei M. 1987. Molecular Evolutionary Genetics. Columbia University Press, New York, USA. DOI: https://doi.org/10.7312/nei-92038
Payne L N and Venugopal K. 2000. Neoplastic diseases: Marek’s disease, avian leukosis and reticuloendotheliosis. Scientific and Technical Review of the Office International des Epizooties 19(2): 544–64. DOI: https://doi.org/10.20506/rst.19.2.1226
Yang J, Yu Y, Yao J, Chen Y, Xu G, Yang N, Sun D and Zhang Y. 2011. Molecular identification of avian leukosis virus subgroup E. loci and tumour virus B locus in Chinese indigenous chickens. Poultry Science 90(4): 759–65. DOI: https://doi.org/10.3382/ps.2010-01133
Yeh F C, Yang R C, Boyle T, Ye Z-H, Yeh D and Mao J X. 1997. POPGENE, the user-friendly shareware for population genetic analysis. Molecular Biology and Biotechnology Centre, University of Alberta, Canada.
Yu J C, Ning Z H and Bao M. 2012. Genetic variation at the TVB locus in Chinese native Chicken breeds. Journal of Animal and Veterinary Advances 11(22): 4226–29.
Zhang H M, Bacon L D, Cheng H H and Hunt H D. 2005. Development and validation of a PCR-RFLP assay to evaluate TVB haplotypes coding receptors for subgroup B and subgroup E avian leukosis viruses in White Leghorns. Avian Pathology 34(4): 324–31. DOI: https://doi.org/10.1080/03079450500179491
Zhang H M, Bacon L D, Heidari M, Muir W M, Groenen M A, Zhang Y, Wong G K S, Fulton J E, O’Sullivan N P, Albers G A A, Vereijken A L J, Rattink A P, Okimoto R, McKayJ C, McLeod S and Cheng H H. 2007. Genetic variation at the tumour virus B locus in commercial and laboratory chicken populations assessed by a medium-throughput or a highthroughput assay. Avian Pathology 36(4): 283–91. DOI: https://doi.org/10.1080/03079450701449248
Downloads
Submitted
Published
Issue
Section
License
The copyright of the articles published in The Indian Journal of Animal Sciences is vested with the Indian Council of Agricultural Research, which reserves the right to enter into any agreement with any organization in India or abroad, for reprography, photocopying, storage and dissemination of information. The Council has no objection to using the material, provided the information is not being utilized for commercial purposes and wherever the information is being used, proper credit is given to ICAR.
How to Cite
