SUCCESSFUL AUTOVACCINE THERAPY FOR CANINE ORAL PAPILLOMATOSIS
Keywords:
Oral papilloma, Dog,, Autovaccine, CPV 1Abstract
Canine oral papillomatosis is a contagious and spontaneously regressing benign neoplastic disease of young dogs caused by canine oral papillomavirus. Six dogs of different breeds aged between 1-3 years were presented to Veterinary Clinical Complex with the history of wart like lesions in different parts of the oral cavity. Under Xylazine sedation and 10 % Lignocaine spray representative biopsy sample of wart was surgically excised. Autogenous vaccine was developed and mixed with formalin solution to in activate the virus. Dogs were subjected to inj. Autovaccine 1 ml through subcutaneous route once in a week for 5 weeks. Warts were completely regressed within 4 weeks period after autoimmune therapy. There was no recurrence of papillomatosis among the treated dogs during the follow-up period of 6 months and no adverse effects were recorded.
Downloads
References
Agut, M., Bayo, M., Larrondo, J. and Calvo, M. A. (1996). Auto-vaccination as a treatment in canine papillomavirus dermatological disease: a study of nine cases. Biomedical Letters, 54(213): 23-26.
Bernard, H.U., Burk, R.D., Chen, Z., Van Doorslaer, K., ZurHausen, H. and De Villiers, E.M. (2010). Classification of papillomaviruses (PVs) based on 189 PV types and proposal of taxonomic Amendments. Virology, 401: 70–79.
Gross, T.L., Ihrke, P.J., Walder, E. J. and Affolter, V. K. (2005). Skin Diseases of the Dog and Cat: Clinical and histopathologic diagnosis. 2nd ed. Blackwell, Oxford.pp: 932.
Heather E. Lane, Scott Weese, J. and Jason W. Stull (2017). Canine oral papillomavirus outbreak at a dog daycare facility. Canadian Veterinary Journal, 58(7): 747–749
Lange, C.E. and Favrot, C. (2011). Canine papilloma viruses. Veterinary Clinical North American Small Animal Practice, 41: 1183–1195.
Miller, W.H., Griffin, C.E. and Campbell, K.L. (2012). Viral, Rickettsial, and Protozoal Skin Diseases. In Muller and Kirk’s Small Animal Dermatology. 7th ed. Philadelphia, pp: 349
Tuddow Thai wong, Dodd G. Sledge, Annabel G. Wise, Katherine Olstad, Roger, K. Maes and MattiKiupel. (2018). Malignant transformation of canine oral papillomavirus (CPV1)-associated papillomas in dogs: An emerging concern? Papillomavirus Research, 6: 83–89.
Uwagie-Ero., Edwin Aihanuwa, Abiaezute, Clifford Nwabugwu., Odigie Eugene, Aimienwanlen and O’kwuAudu James. (2017). Management of Canine Papillomatosis using Oral Acyclovir – A Case Report. International Journal of Veterinary Science, 6(4): 187-190.
Yagci, B.B., Ural, K., Ocal, N. and Haydardedeoglu, A. E. (2008). Azithromycin therapy of papillomatosis in dogs: a prospective, randomized, double-blinded, placebo-controlled clinicaltrial. Veterinary Dermatology, 19: 194- 198.
Downloads
Published
Issue
Section
License
All the copy right belongs to the sponsoring Organization, Tamil Nadu Veterinary and Animal Sciences University, Chennai - 51.