EFFECT OF TINOSPORA CORDIFOLIA ON MCF-7 CELL MORPHOLOGY

Authors

  • M. Sakthi Priya Krishi Vigyan Kendra, Veterinary College and Research Institute, Namakkal - 637 002
  • K.V. Venkateswaran Krishi Vigyan Kendra, Veterinary College and Research Institute, Namakkal - 637 002
  • T. Vijayanand Krishi Vigyan Kendra, Veterinary College and Research Institute, Namakkal - 637 002

DOI:

https://doi.org/10.56093/ijvasr.v43i3.152926

Keywords:

Tinospora cordifolia, MCF-7cell line, Degenerative changes, Doses

Abstract

The study of the influence of aqueous and hydro alcoholic extracts of Tinospora cordifolia on human mammary tumor cell line MCF-7 is a common way of discovering potential therapeutics for treating people suffering from hormone-dependent problems and diseases. In the present study, the cells were treated with the extracts at three different doses viz., 200 μg/ml, 400 μg/ ml and 600 μg/ml. Both the extracts produced degenerative changes in the cell in dose-dependent manner with maximum effect being noticed at the dose level of 600 μg/ml. Thus, these findings suggest that the extracts from Tinospora cordifolia have potential for acting as an antiproliferative agent in mammary tumour. 

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References

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Published

08-08-2024

Issue

Vol. 43 No. 3 (2014): IJVASR May - June 2014

Section

Short Communications

License

All the copy right belongs to the sponsoring Organization, Tamil Nadu Veterinary and Animal Sciences University, Chennai - 51.

How to Cite

M. Sakthi Priya, K.V. Venkateswaran, & T. Vijayanand. (2024). EFFECT OF TINOSPORA CORDIFOLIA ON MCF-7 CELL MORPHOLOGY. Indian Journal of Veterinary and Animal Sciences Research, 43(3), 239-242. https://doi.org/10.56093/ijvasr.v43i3.152926