ANTIBACTERIAL  SUSCEPTIBILITY  PROFILES  OF COLIFORMS ISOLATED FROM  BOVINE  SUBCLINICAL  AND CLINICAL  MASTITIS AGAINST  FLUOROQUINOLONES

K. Saranya; S. Pavulraj; L. Kalaiselvi; S. Amsaveni; S. Ramesh

doi:10.56093/ijvasr.v9i4.156321

Authors

K. Saranya Department of Veterinary Pharmacology and Toxicology, Madras Veterinary College, Chennai-600 007
S. Pavulraj Department of Veterinary Pharmacology and Toxicology, Madras Veterinary College, Chennai-600 007
L. Kalaiselvi Department of Veterinary Pharmacology and Toxicology Madras Veterinary College, Chennai-600 007
S. Amsaveni Department of Veterinary Pharmacology and Toxicology, Madras Veterinary College, Chennai-600 007
S. Ramesh Department of Veterinary Pharmacology and Toxicology, Madras Veterinary College, Chennai-600 007

https://doi.org/10.56093/ijvasr.v9i4.156321

Keywords:

Mastitis, Coliforms, Escherichia coli, Antimicrobial resistance, Fluoroquinolones

Abstract

The primary objective of this study was to assess the antibacterial sensitivity pattern of Coliforms isolates from clinical and sub-clinical mastitis to quinolones. Forty coliforms isolates from bovine clinical and subclinical mastitis were tested for antimicrobial susceptibility by measuring MIC by Resazurin dye broth microdilution method. Of the 27 E. coli isolates tested, only 7.4% of the isolates were found to be susceptible to ofloxacin and 7.37, 55.55 and 59.25% of isolates were found to be resistant to ciprofloxacin, enrofloxacin and ofloxacin, respectively. The proportion of coliform isolates other than E. coli resistant to fluoroquinolones tested were 30-47%. The result of this study indicates the presence of high level of resistance of coliforms against fluoroquinolones. This necessitates routine monitoring of resistance pattern among field isolates of mastitis and to develop suitable antimicrobial usage policy.

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