ANTIMICROBIAL, ANTIFUNGAL AND ANTIOXIDANT ACTIVITY OF AQUEOUS EXTRACT OF SYZGIUM CUMINI LEAF


196 / 124

Authors

  • M. Dhanasekaran PG Scholar, Department of Food Safety and Quality Assurance, College of Food and Dairy Technology, TANUVAS, Koduveli, Chennai - 600 052.
  • I. Manikkavasagan Assistant Professor, Department of Food Safety and Quality Assurance, College of Food and Dairy Technology, TANUVAS, Koduvalli, Chennai - 52.
  • S. Meignanalakshmi Professor, Department of Animal Biotechnology, Madras Veterinary College, TANUVAS, Chennai
  • G.M. Sivakumar Professor, Department of Food Safety and Quality Assuarance, College of Food and Dairy Technology, TANUVAS, Koduveli, Chennai - 600 052

https://doi.org/10.56093/ijvasr.v55i1.175144

Keywords:

Syzygium cumini, antimicrobial activity, antifungal activity, antioxidant activity

Abstract

In the present study, the phytochemical constituents of Syzygium cumini (Naval) leaf extract were analyzed, and its antibacterial, antifungal, and antioxidant activities were evaluated. The phytochemical screening shown the presence of alkaloids, phenols, flavonoids, tannins, glycosides, and saponins in the extract. Antibacterial and antifungal activities were evaluated against Escherichia coli, Staphylococcus aureus, and  Aspergillus  flavus using  the  agar  well  diffusion  method,  which  showed  clear dose-dependent inhibition of the selected organisms.The zone diameters indicating antibacterial activity ranged from 1.3 to 1.8cm against Escherichia coli and from 1.0 to 1.6 cm against Staphylococcus aureus. In addition, the zone diameters for antifungal activity against Aspergillus flavus were observed to range between 1.2 and 1.6 cm. The antioxidant activity of the leaf extract demonstrated substantial free radical scavenging potential, reaching its maximum effect at 250 µg/ml is 61.32±0.44%. The aqueous leaf extract of Syzygium cumini exhibits strong antioxidant and antimicrobial properties.

 

Downloads

Download data is not yet available.

References

Abdulrahman, M.D., (2022). Review of Ethnopharmacology, Morpho- Anatomy, Biological Evaluation and Chemical Composition of Syzygium polyanthum (Wight) Walp. Plant Science Today, 9(1):167-177.

Abdulrahman, M.D., Ali, A., Fatihah, H.N.N., Khandaker, M.M. and Mat, N., (2018). Morphological and anatomical Studies of Syzygium polyanthum (Wight) Walp.(Myrtaceae). Malayan Nature Journal, 70(3).

Adil, M., Filimban, F.Z., Ambrin, Quddoos, A., Sher, A.A. and Naseer, M., (2024). Phytochemical screening, HPLC analysis, antimicrobial and antioxidant effect of Euphorbia parviflora L.(Euphorbiaceae Juss.). Scientific reports, 14(1):5627.

Chandrasekaran, M. and Venkatesalu, V., (2004). Antibacterial and antifungal activity of Syzygium jambolanum seeds. Journal of ethnopharmacology, 91(1):105-108.

Chua, L.K., Lim, C.L., Ling, A.P.K., Chye, S.M. and Koh, R.Y., (2019). Anticancer potential of Syzygium species: a review. Plant Foods for Human Nutrition, 74(1) : 18-27.

Da Rosa, A.C.S., Hoscheid, J., Garcia, V.A.D.S., de Oliveira Santos Junior, O. and da Silva, C. (2024). Phytochemical Extract from Syzygium cumini Leaf: Maximization of Compound Extraction, Chemical Characterization, Antidiabetic and Antibacterial Activity, and Cell Viability. Processes, 12(10): 2270.

Devi, H.J., Gnanasekaran, P., Devi, Y.A., Saravanan, D., Gopal, T., Balakumar, V., Sathish, P., Nataraja, K., Sundar, B.K.J. and Femi, F.D. (2025). Comparative efficacy of Syzygium cumini leaf extract and chemical disinfectants against hospital floor isolates: First report of benzalkonium chloride-resistant Mucor sp. Journal of Applied Pharmaceutical Science, 15(11): 154-168.

Fiqri, H., Arda, A.G., Adrebi, K., Proborini, W.D. and Widyanto, R.M. (2020), October. Evaluation of total phenolic, total flavonoid, and in vitro cytotoxic activity of Syzygium cumini extract in cervical cancer cell. In Journal of Physics: Conference Series, 1665(1): 012033). IOP Publishing.

Imran, M., Imran, M. and Khan, S. (2017). Antibacterial activity of Syzigium cumini leaf extracts against multidrug resistant pathogenic bacteria. Journal of Applied Pharmaceutical Science, 7(3) :168-174.

Jabeen, K. and Javaid, A. (2010). Antifungal activity of Syzygium cumini against Ascochyta rabiei–the cause of chickpea blight. Natural product research, 24(12) : 1158-1167.

Kadlag, P.R. (2023). Preliminary phytochemical evaluation of Syzygium cumini (L.) Skeels leaves. Anveshana’s International Journal of Research and Engineering Applied Sciences, 8(2) : 49-51.

Lima, L.A., Siani, A.C., Brito, F.A., Sampaio, A.L.F., Henriques, M.D.G.M.O. and Riehl, C.A.D.S. (2007). Correlation of anti-inflammatory activity with phenolic content in the leaves of Syzygium cumini (L.) Skeels (Myrtaceae). Química Nova, 30 : 860- 864.

R.N., Hingmire, P.M. and Jadhav, D.M. (2024). Primary phytochemical and pharmacognostic studies on Syzygium cumini Linn.(Jambhul). Journal of Pharmacognosy and Phytochemistry, 13(1): 299-305.

Naiel, B., Fawzy, M., Mahmoud, A.E.D. and Halmy, M.W.A. (2024). Sustainable fabrication of dimorphic plant derived ZnO nanoparticles and exploration of their biomedical and environmental potentialities. Scientific Reports, 14(1):13459.

Oliveira, G.F.D., Furtado, N.A.J.C., Silva Filho, A.A.D., Martins, C.H.G., Bastos, J.K., Cunha, W.R. and Silva, M.L.D.A. (2007). Antimicrobial activity of Syzygium cumini (Myrtaceae) leaves extract. Brazilian Journal of Microbiology, 38: 381-384.

Rayzah, M., Elderdery, A.Y., Alzerwi, N.A., Alzahrani, B., Alsrhani, A., Alsultan, A., Idrees, B., Rayzah, F., Bakhsh, Y., Alzahrani, A.M. and Subbiah, S.K., (2023). Syzygium cumini (L.) Extract- Derived Green Titanium Dioxide Nanoparticles Induce Caspase- Dependent Apoptosis in Hepatic Cancer Cells. Plants, 12(18): 3174.

Roy, M., Roy, S., Roopali, B., Ottalwar, N., Singh, N. and Singh, J. (2020). Phytochemical characterization of different extracts isolated from Tamarindus indica L. in and around Durg District of Chhattisgarh State, India. Intermational Journal of Currernt Microbiology Applied Sciences, 9(3): 2819-2824.

Ruan, Z.P., Zhang, L.L. and Lin, Y.M. (2008). Evaluation of the antioxidant activity of Syzygium cumini leaves. Molecules, 13(10): 2545-2556.

Shidiki, A. and Vyas, A. (2022). Molecular docking and pharmacokinetic prediction of phytochemicals from Syzygium cumini in interaction with penicillin-binding protein 2a and erythromycin ribosomal methylase of Staphylococcus aureus. Biotechnologia, 103(1): 5-18.

Downloads

Submitted

13-01-2026

Published

19-01-2026

How to Cite

M. Dhanasekaran, I. Manikkavasagan, S. Meignanalakshmi, & G.M. Sivakumar. (2026). ANTIMICROBIAL, ANTIFUNGAL AND ANTIOXIDANT ACTIVITY OF AQUEOUS EXTRACT OF SYZGIUM CUMINI LEAF. Indian Journal of Veterinary and Animal Sciences Research, 55(1), 77-86. https://doi.org/10.56093/ijvasr.v55i1.175144
Citation