ANTIMICROBIAL ACTIVITY AND PHYTOCHEMICAL SCREENING OF THE PEEL EXTRACTS OF Luffa acutangula
296 / 342
Keywords:
Luffa acutangula, Phytochemicals, Antimicrobial activity, FT–IR spectroscopyAbstract
The study was conducted to evaluate the antimicrobial and phytochemical activities of the peel extracts of
Luffa acutangula. The antimicrobial activity of aqueous, petroleum ether, acetone and chloroform peel extracts
was tested against the selected bacterial and fungal isolates using agar well diffusion method. The results
proved that the acetone extract exhibited maximum antimicrobial activity against the tested bacterial and fungal
isolates when compared to chloramphenicol and flucanazole (standard antibiotics) respectively. Preliminary
phytochemical screening was carried out in the acetone extract of L. acutangula which revealed the presence
of secondary metabolites such as saponins, phenols, terpenoids, tannins, flavonoids, sterols, anthocyanin,
carbohydrates and amino acids. The FT-IR analysis revealed the presence of hydroxyl, amines and carboxylic
acids as functional groups in L. acutangula.
References
Abirami, S., Nishanthini, K and Poonkothai, M.
Antimicrobial activity and
phytochemical screening of the leaf
extracts of Eucalyptus globulus.
International Journal of Current
Pharmaceutical Research. 9(5): 85-89.
Andrade, S., Ramalho, M. J., Loureiro, J. A and
Pereira, M. C. 2019. Natural compounds
for Alzheimer’s disease therapy: A
systematic review of preclinical and clinical
studies. International Journal of Molecular
Sciences. 20 (2313): 1- 41.
Anitha, J and Miruthula, S. 2014. Traditional
medicinal uses, phytochemical profile and
pharmacological activities of Luffa
acutangula Linn. International Journal of
Pharmacognosy. 1(3): 174-83.
Bauer, A. W., Kirby,W. M. M., Sherris, J.C and
Turck, M. 1966. Antibiotic susceptibility
testing by a standardized single disk
method. American Journal of Clinical
Pathology. 36: 493-496.
Begum, R and Poonkothai, M. 2013. In-vitro
antimicrobial activity and phytochemical
analysis of Brassica oleracea. International
Journal of Pharmacy and Pharmaceutical
Sciences. 5(2): 405-408.
Ceylan, E and Fung, D.Y.C. 2004. Antimicrobial
NETHRA and POONKOTHAI
activity of spices. Journal of Rapid Methods
and Automation in Microbiology. 12 (1): 1 –
Dutt, R., Garg, V., Khatri, N and Madan, A.K.
Phytochemicals in anticancer drug
development. Anti - Cancer Agents in
Medicinal Chemistry. 19(2): 172–183.
Fasuyi, A.O. 2006. Nutritional potentials of some
tropical vegetable leaf meals: chemical
characterization and functional properties.
African Journal of Biotechnology. 5(1): 49-
Harborne, J.B. 1984. Phytochemical Methods -
A Guide to Modern Techniques of Plant
Analysis. 2nd Edition, Chapman and Hall,
London, USA. pp. 279.
Manikandaselvi, V., Vadivel, P and Brindha, S.
Review on Luffa acutangula L.:
Ethnobotany, phytochemistry, nutritional
value and pharmacological properties.
International Journal of Current
Pharmaceutical Review and Research.
(3): 151-155.
Onwuliri, F.E and Wonang, D.L. 2005. Studies
on the combined antibacterial action of
ginger (Zingiber officiale L.) and garlic
(Allivum sativum L.) on some bacteria.
Nigerian Journal of Botany. 18: 224 – 228.
Passamonti, S., Vrhovsek, U., Vanzo , A and
Mattivi , F. 2003. The stomach as a site for
anthocyanins absorption from food. FEBS
Letters. 544(1-3): 210 - 213.
Semwal, P. and Painuli, S. 2019. Antioxidant,
antimicrobial and GC-MS profiling of
Saussurea obvallata (Brahma Kamal) from
Uttarakhand Himalaya. Clinical Phytoscience.
:12: 1-11.
Sharma, M., Moha, V., Abraham, M and
Sharma, M. 2010. Antimicrobial potential
of the phytoextracts of some Nyctaginaceae
members. African Journal of
Biotechnology. 9(46): 7942 - 7947.
Downloads
Submitted
Published
Issue
Section
License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The author owns the article's copyright until the article is accepted for publication. After acceptance, the author(s) assigns the article's copyright jointly to both the authors and the Publishers of the Journal of Research ANGRAU (ANGRAU) and licensed under a Creative Commons Attribution-Non Commercial-Share Alike 4.0 International License.