ANTIMICROBIAL ACTIVITY AND PHYTOCHEMICAL SCREENING OF THE PEEL EXTRACTS OF Luffa acutangula
374 / 342
Keywords:
Luffa acutangula, Phytochemicals, Antimicrobial activity, FT–IR spectroscopyAbstract
The study was conducted to evaluate the antimicrobial and phytochemical activities of the peel extracts of
Luffa acutangula. The antimicrobial activity of aqueous, petroleum ether, acetone and chloroform peel extracts
was tested against the selected bacterial and fungal isolates using agar well diffusion method. The results
proved that the acetone extract exhibited maximum antimicrobial activity against the tested bacterial and fungal
isolates when compared to chloramphenicol and flucanazole (standard antibiotics) respectively. Preliminary
phytochemical screening was carried out in the acetone extract of L. acutangula which revealed the presence
of secondary metabolites such as saponins, phenols, terpenoids, tannins, flavonoids, sterols, anthocyanin,
carbohydrates and amino acids. The FT-IR analysis revealed the presence of hydroxyl, amines and carboxylic
acids as functional groups in L. acutangula.
References
1. Abirami, S., Nishanthini, K and Poonkothai, M.
2. Antimicrobial activity and
3. phytochemical screening of the leaf
4. extracts of Eucalyptus globulus.
5. International Journal of Current
6. Pharmaceutical Research. 9(5): 85-89.
7. Andrade, S., Ramalho, M. J., Loureiro, J. A and
8. Pereira, M. C. 2019. Natural compounds
9. for Alzheimer’s disease therapy: A
10. systematic review of preclinical and clinical
11. studies. International Journal of Molecular
12. Sciences. 20 (2313): 1- 41.
13. Anitha, J and Miruthula, S. 2014. Traditional
14. medicinal uses, phytochemical profile and
15. pharmacological activities of Luffa
16. acutangula Linn. International Journal of
17. Pharmacognosy. 1(3): 174-83.
18. Bauer, A. W., Kirby,W. M. M., Sherris, J.C and
19. Turck, M. 1966. Antibiotic susceptibility
20. testing by a standardized single disk
21. method. American Journal of Clinical
22. Pathology. 36: 493-496.
23. Begum, R and Poonkothai, M. 2013. In-vitro
24. antimicrobial activity and phytochemical
25. analysis of Brassica oleracea. International
26. Journal of Pharmacy and Pharmaceutical
27. Sciences. 5(2): 405-408.
28. Ceylan, E and Fung, D.Y.C. 2004. Antimicrobial
29. NETHRA and POONKOTHAI
30. activity of spices. Journal of Rapid Methods
31. and Automation in Microbiology. 12 (1): 1 –
32. Dutt, R., Garg, V., Khatri, N and Madan, A.K.
33. Phytochemicals in anticancer drug
34. development. Anti - Cancer Agents in
35. Medicinal Chemistry. 19(2): 172–183.
36. Fasuyi, A.O. 2006. Nutritional potentials of some
37. tropical vegetable leaf meals: chemical
38. characterization and functional properties.
39. African Journal of Biotechnology. 5(1): 49-
40. Harborne, J.B. 1984. Phytochemical Methods -
41. A Guide to Modern Techniques of Plant
42. Analysis. 2nd Edition, Chapman and Hall,
43. London, USA. pp. 279.
44. Manikandaselvi, V., Vadivel, P and Brindha, S.
45. Review on Luffa acutangula L.:
46. Ethnobotany, phytochemistry, nutritional
47. value and pharmacological properties.
48. International Journal of Current
49. Pharmaceutical Review and Research.
50. (3): 151-155.
51. Onwuliri, F.E and Wonang, D.L. 2005. Studies
52. on the combined antibacterial action of
53. ginger (Zingiber officiale L.) and garlic
54. (Allivum sativum L.) on some bacteria.
55. Nigerian Journal of Botany. 18: 224 – 228.
56. Passamonti, S., Vrhovsek, U., Vanzo , A and
57. Mattivi , F. 2003. The stomach as a site for
58. anthocyanins absorption from food. FEBS
59. Letters. 544(1-3): 210 - 213.
60. Semwal, P. and Painuli, S. 2019. Antioxidant,
61. antimicrobial and GC-MS profiling of
62. Saussurea obvallata (Brahma Kamal) from
63. Uttarakhand Himalaya. Clinical Phytoscience.
64. :12: 1-11.
65. Sharma, M., Moha, V., Abraham, M and
66. Sharma, M. 2010. Antimicrobial potential
67. of the phytoextracts of some Nyctaginaceae
68. members. African Journal of
69. Biotechnology. 9(46): 7942 - 7947.
Downloads
Published
Issue
Section
License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The author owns the article's copyright until the article is accepted for publication. After acceptance, the author(s) assigns the article's copyright jointly to both the authors and the Publishers of the Journal of Research ANGRAU (ANGRAU) and licensed under a Creative Commons Attribution-Non Commercial-Share Alike 4.0 International License.