High level transferable resistance among Escherichia coli


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Authors

  • IQBAL AHMAD
  • J N S YADAVA
  • SHAMIM AHMAD

Abstract

Escherichia coli strains (48) isolated from clinical cases of man and animals were screened for their antibiotic resistance profile and their potential to exchange their chromosomal chromosomal genetic materials (R-plasmids). Of these 32 (66.66%) strains were resistant to one or more drugs. Multiple resistance was
observed in 26 (81.56%) strains. Maximum number of strains were resistant to streptomycin (64.41%) followed by ampicillin (56.25%). tetracycline (52.83%). amoxycillin (50%). chloramphenicol (41.66%) and co-trimoxazole (37.31%), and least to kanamycin (10.41 %), nitrofurantoin and nitrofurazone (8.33% each). None of the strans were resistant to nalidixic acid: 13 multi-resistant strams could transfer their drug resistance markers to the recipient E. coli K 12 J 62-1. These transferred R-factors were stable for several generations. Strains possessing single. double or triple drug-resistant markers were mostly non-transferable by conjugation experiments in vitro.

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Author Biographies

  • IQBAL AHMAD
    Senior Research Fellow, Central Drug Research Institute, Lucknow, Uttar Pradesh 226 001

  • J N S YADAVA
    Emeritus Scientist, Division of Microhiology, Central Drug Research Institute, Lucknow, Uttar Pradesh 226 001

  • SHAMIM AHMAD
    Reader, Institute of Ophthalmology. J N Medical
    College, Aligarh Muslim University, Aligarh 200 001.

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Issue

Vol. 64 No. 5 (1994)

Section

Articles

License

The copyright of the articles published in The Indian Journal of Animal Sciences is vested with the Indian Council of Agricultural Research, which reserves the right to enter into any agreement with any organization in India or abroad, for reprography, photocopying, storage and dissemination of information. The Council has no objection to using the material, provided the information is not being utilized for commercial purposes and wherever the information is being used, proper credit is given to ICAR.

How to Cite

AHMAD, I., YADAVA, J. N. S., & AHMAD, S. (2013). High level transferable resistance among Escherichia coli. The Indian Journal of Animal Sciences, 64(5). https://epubs.icar.org.in/index.php/IJAnS/article/view/30579