Characterization of Indian type '0' foot-and·mouth-disease virus isolates using polyclonal and monoclonal antibodies


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Authors

  • C TOSH
  • B PATTNAIK
  • R VENKATARAMANAN

Abstract

Twelve neutralizing monoctonal antibodies (Mabs) to the type '0' foot-and-mouth disease vaccine virus strain (R2/15) were used for characterizing 21 type '0' field isolates in enzyme-linked immunosorbent assay (ELISA). The results obtained with Mabs were compared with those obtained with comp!lement. fixation test, sandwich ELISA and 2-dimensional microneutralization test using polyclonal antibodies. The combined study revealed serological relatedness of all the field isolates with the reference virus.

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Author Biographies

  • C TOSH
    Research Scholar,
  • B PATTNAIK
    Scientist central FMD Virus Typing Laboratory.
  • R VENKATARAMANAN
    Scientist central FMD Virus Typing Laboratory.

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Issue

Vol. 65 No. 4 (1995)

Section

Articles

License

The copyright of the articles published in The Indian Journal of Animal Sciences is vested with the Indian Council of Agricultural Research, which reserves the right to enter into any agreement with any organization in India or abroad, for reprography, photocopying, storage and dissemination of information. The Council has no objection to using the material, provided the information is not being utilized for commercial purposes and wherever the information is being used, proper credit is given to ICAR.

How to Cite

TOSH, C., PATTNAIK, B., & VENKATARAMANAN, R. (2013). Characterization of Indian type ’0’ foot-and·mouth-disease virus isolates using polyclonal and monoclonal antibodies. The Indian Journal of Animal Sciences, 65(4). https://epubs.icar.org.in/index.php/IJAnS/article/view/31645