Histomorphological development of lung in perinatal goat

Abstract

Lungs from 15 Assam local goats were studied at 5 different phases of development, ranging from 116 days (225 mm CRL) prenatal to 30 days postnatal. Developmental stages, viz. late canalicular. terminal sac and alveolar. were identified at 116 days (225 mm CRL), 139 days (250 mm CRL) and 149 days (335 mm CRL) respectively. Rapid histomorphological changes were observed in the lung parenchyma of these foetuses. The lining epithelium of the alveoli was differentiated into type I (squamous) and type II (cuboidal) pneumcyotes at 149 days foetal lung. Neonatal lung at birth demonstrated well developed and distinct alveoli and lypically branched exchange component. The functional hlood-air-barrier was established. The formation of ncw alveoli was the main characteristic feature from birth up to 30 days of age. The conducting components of these lungs revealed an age-associated increase with the advancement of age. The neonatal lung of 30 days old kid almost resem"bled to that of adult goat.