Bacteriological evaluation of urine, bladder mucosal biopsy and uroliths in dogs suffering from urolithiasis

Abstract

Urolithiasis was studied in 9 dogs in which uroliths were present at multiple site in 5 cases, urinary bladder in 3 cases and urethra in 1 case. Either cystotomy or urethrotomy or both were carried out in the urinary tract. Comparative bacterial culture examination of urine, bladder mucosal biopsy and uroliths collected at the time of sugical interventation revealed Escherichia coli, Proteus mirabilis, Staphylococcus spp and Klebsiella pneumoniae infection in different cases. Identical bacteria was isolated from urine, bladder mucosal biopsy and urolith cultures. Antimicrobial sensitivity patterns of different bacteria isolated indicated that tobramycin, amikacin, cefazolin and ciprofloxacin were the most sensitive antibiotics. Oxytetracyclin and nalidixic acid were the most resistant antibiotics. Antimicrobial therapy based on CST helped in effective planning of postoperative management in prevention of recurrence of canine urolithiasis.