Treatment of placental retention with ecbolic drugs and its effect on subsequent fertility in crossbred cows

Abstract

This study was conducted to examine the fertility response tn cows with retained fetal membranes (RFM) following treatment with ecbolic drugs. Dairy cows (n=32) that had RFM more than 12 hr after parturition were randomly assigned to 1 of 4 treatment groups; group l,daily intrauterillr infusion of 4 oriprim bolus until membranes were expelled and i.m. injections of 30 IU synotocinon, 15 mg luprostiol plus 10 mg estradiol valerate; group 2, oriprim as similar to group 1 and oxytetracycline injections; group 3, oriprim as in groups I and 2 plus a herbal drug, 20 g metrali daily for 5 days and group 4 served as untreated controls. Cows were monitored dally. Subsequent disease conditions were recorded. The blood samples were collected from all cows for determination vf biochemical parameters and hormonal profile. The results revealed that the interval from parturition to expUlsion of fetal membranes was unaffected by treatment regimen. Reproductive efficiency, as determined on the basis of the interval from parturition to conception (136.8 ± 26.3 day) and number of services per conception (3.0± 0,50) was significantly better in group I than that of control cows. The study also showed that globulins and immunoglobulins levels were higher in RFM cows. Significant increase in serum alkaline phosphatase and lactic dehydrogenase levels in RFM cows suggested that estimation of these biochemical parameters would have prognostic value in postpartum complications. It may be concluded that the administration of ecbolic drugs in cows with RFM may hasten the resumption of normal reproductive activity.