Sedivet as a premedicant in barbiturate and nonbarbiturate anaesthesia in goats

Abstract

Sedivet administered @12.5 µg/kg IV average weak time of 55.0±22.5 sec. Along with behavioural changes were observed on IV administration of sedivet (12.5 µg/kg) in atropine (0.5 mg/kg,sc) pre-medicated goats. Increased salivation was noticed during experimentation. Corneal palpebral, pharyngeal and laryngeal reflexes were mildly depressed (++) in group B while they were absent in group A during anaesthesia. Analgesia in flank in group B persisted for 80.39±31.85 min and in group A for 50.83±20.30 min. Poly urea occurred in both the groups. Marked reduction in rectal temperature, heart rate and respiration rate was noticed in sedivet ketamine group. ABP and CVP increased significantly at 2 min of sedivet injection. TEC,TLC, PCV, HB altered nonsignificantly. Serum glucose, bilirubin, urea, SUN and OCT exhibited significant rise (P<0.05) at different intervals while total proteins, albumin, globulin and A:G ratio were slightly lower at 1 hr. Haematobiochemical parameters were recorded close to base value at 72 hr. Recovery was smooth and uncomplicated.