Effect of extreme hot climate on liver and serum enzymes in Marwari goats

Abstract

A study was conducted to investigate liver and serum enzymes i.e. aspartate amino transferase (AST) and alanine amino transferase (ALT) during moderate (Jan/Feb) and extreme (May/ June) climatic conditions in three hundred Marwari goats. In each climatic condition, 150 animals were taken. They were categorized in to males (70 of 0-1 year, and 30 of above 1 year) and females (30 of 0-1 year, and 20 of above 1 year). Blood samples were collected aseptically using EDTA containing vials and after separation of serum the serum transaminases were determined. Liver tissues were collected after slaughter of the animal and all the analyses were carried out at the same day of collection of fresh sample. Liver AST and ALT (IU/L) ranged from 210.56 to 610.10 (average 579.65±11.33) and from 170.11 to 562.70 (average 402.09±21.34), respectively. Serum AST and ALT ranged from 56.70 to 215.00 (average 186.76±7.87) and from 20.15 to 85.77 (average 57.54±1.24), respectively. Season had significant (P<0.05) effect on both liver and serum ALT. Liver ALT showed significant (P<0.05) effect on sex in both climatic conditions and age group in moderate climatic condition. Higher values were observed in liver AST and ALT in males in comparison to females in both climatic conditions. Higher values of liver AST and ALT were observed in 0–1 year age group animals than above 1 year age group in both climatic conditions except in extreme climatic condition values of ALT observed higher in above 1 year age group animals. Serum AST showed significant (P<0.05) effect of sex in both climatic conditions but mean while, serum ALT showed significant (P<0.05) effect on age group in extreme climatic condition only. Higher values of serum AST was observed in male while serum ALT values were higher in female of both climatic conditions.