Blood biochemical and uterine tissue alterations in relation to duration of dystocia in caesarean-operated bovines

Abstract

The present study was undertaken to assess some biochemical and uterine histopathological alterations in 41 dystocia affected bovines. The animals were divided into 3 groups, viz. with occurrence of labour pains for <12h (group A; n=12), 12–36h (group B; n=11) and >36h (group C; n=18). Pre-caesarean concentrations of blood histamine, serum ceruloplasmin and plasma creatine kinase were significantly higher in group C in comparison to group A. Concentrations of serum ceruloplasmin and plasma creatine kinase remained elevated during post-caesarean period in animals of group C compared to group A. Uterine histopathology of dystocia affected bovines revealed severe damage to epithelial/ subepithelial, muscular and endometrial glands with increase in duration of dystocia, whereas, superficial inflammatory changes were chronic in delayed cases. In conclusion, elevated blood histamine, serum ceruloplasmin and plasma creatine kinase along with severe uterine damage in delayed cases of dystocia indicated progression towards severe inflammation, stress and possibly peritoneal adhesion formation.