Histoenzymic distribution of phosphatases in liver due to experimental lead toxicosis in buffalo (Bubalus bubalis)


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Authors

  • Anuradha Anuradha Punjab Agricultural University, Ludhiana, Puniab
  • Neelam Bansal Punjab Agricultural University, Ludhiana, Puniab
  • Varinder Uppal Punjab Agricultural University, Ludhiana, Puniab

Keywords:

Buffalo, Enzyme, Lead toxicity, Liver

Abstract

The histoenzymic studies were done on 6 crossbred buffalo calves. Experimental lead toxicosis was induced by administering lead acetate @25 mg/kg body weight per os for 7 days. All calves showed symptoms of lead toxicity and died with 6 to 8 days of experiment. The tissue samples from liver were collected and stored in liquid nitrogen. Cryostate section of 10 µm thickness were obtained and incubated for phosphatases. The study revealed moderate ACPase and ATPase and total loss of G-6-Pase activity in hepatocytes while strong ACPase and AKPase activity was observed in Von Kupffer cells.

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Submitted

2011-08-01

Published

2005-07-05

Issue

Vol. 75 No. 7 (2005)

Section

Articles

License

The copyright of the articles published in The Indian Journal of Animal Sciences is vested with the Indian Council of Agricultural Research, which reserves the right to enter into any agreement with any organization in India or abroad, for reprography, photocopying, storage and dissemination of information. The Council has no objection to using the material, provided the information is not being utilized for commercial purposes and wherever the information is being used, proper credit is given to ICAR.

How to Cite

Anuradha, A., Bansal, N., & Uppal, V. (2005). Histoenzymic distribution of phosphatases in liver due to experimental lead toxicosis in buffalo (Bubalus bubalis). The Indian Journal of Animal Sciences, 75(7). https://epubs.icar.org.in/index.php/IJAnS/article/view/8157