Comparative evaluation of endogenous and exogenous creatinine clearance for assessment of glomerular filtration rates in buffalo calves


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Authors

  • S K Rastogi Govind Ballabh Pant University of Agriculture and Technology, Pantnagar, Uttaranchal
  • M Mohsin Govind Ballabh Pant University of Agriculture and Technology, Pantnagar, Uttaranchal

Keywords:

Buffalo, Glomerular filtration rate, Kidney function tests, Renal clearance

Abstract

Female buffalo calves (4) were studied for renal clearance of endogenous and exogenous (creatinine infused @ 15.0 mg/ kg and 40.0 mg/kg body wt) creatinine clearance and compared with inulin clearance. Both dose rates provided better estimates with respective values of glomerulal filtration rates (GFR) 187.7±9.0, 211.O±6.6 ml/min. Respective values for endogenous creatinine and insulin clearance were 203.0±8.8 and 180.1±7.0 ml/min. Creatinine clearance at low dose rate level gave better significant positive correlation (r=0.845)compared to higher dose rate level (r=0.187),which was non-significant. Data indicated that infusion of exogenous creatinine at 15.0 mg/kg body weight could be used to assess glomerular filtration rate in buffalo calves in place of more tedious and cumbersome inulin clearance.

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Submitted

2011-08-02

Published

2005-10-05

Issue

Section

Articles

How to Cite

Rastogi, S. K., & Mohsin, M. (2005). Comparative evaluation of endogenous and exogenous creatinine clearance for assessment of glomerular filtration rates in buffalo calves. The Indian Journal of Animal Sciences, 75(10). https://epubs.icar.org.in/index.php/IJAnS/article/view/8278