Radiological and histopathological alterations in bones in molybdenum-induced hypocuprosis in buffalo calves

Abstract

Hypocuprosis was achieved in 13 buffalo calves by administering 20% solution df ammoniun molybdate in water @ 15 mg Mo/kg body weight for 3 days, followed by 7.5 mg Mo/kg body weight for 4 days and then 51mg Mo/kg b. wt for further 38 days. The clinical findings observed in the bones were stiffness of limbs with enlargement of,joints adjacent to long bone. Radiographically, marked widening of cartilaginous growth plate of metacarpal and slight lipping was recorded Histopathologically, bones revealed osteoporotic changes in the bony spicules along with irregular and disruptive development of growth plates at costochondral junctions.